Marathon running may reverse a risky part of the aging process

Sports Medicine

People have long been aware of the benefits of exercise. Now, a new study finds that one particular aspect of fitness — that is, training for a specific goal — may be particularly advantageous.

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A new study has shown that training for and running a marathon can reverse vascular aging.

The value of goal-oriented exercise ties directly into the aging process. As a person gets older, their arteries are more likely to stiffen.

Aerobic exercise can reduce arterial stiffening, which the medical community sees as a predictor of cardiovascular events.

However, it is difficult for doctors to recommend a form of fitness that is likely to work for everyone.

Recent findings, however, suggest that training for and running a marathon could be an excellent choice for people looking to improve their cardiovascular health.

A total of 138 people running in the 2016 and 2017 London Marathons participated in the study, which appears in the Journal of the American College of Cardiology.

Training for the marathon

None of the participants had completed a marathon before, and none had any significant medical history or preexisting heart disease.

They were also all running a maximum of 2 hours a week before starting the study.

Just over half of the participants were female, with the average age of the group being 37 years.

The researchers advised each of the runners to follow the marathon’s Beginner’s Training Plan, which consists of about three runs every week for 17 weeks leading up to the race.

As the weeks went on, the weekly exercise became more intense.

A 4 year reduction

Before the participants began their marathon training, the research team measured their blood pressure and aortic stiffness using cardiovascular magnetic resonance.

The researchers calculated the biological age of each individual’s aorta using their actual age and the aortic stiffness measurements from three levels of the artery.

They then took the same measurements between 1 and 3 weeks after the marathon.

An analysis of the average finish times of 27,000 runners suggested that the participants were running between 6 and 13 miles a week in training.

Of the participants, the men took an average of 4.5 hours to complete the race while the women took 5.4 hours.

When the researchers compared the measurements from before and after the race, they found that both blood pressure and aortic stiffness had reduced in the first-time marathon runners.

Notably, the changes in aortic stiffness were equivalent to a 4 year decrease in vascular age.

Interestingly, older male runners who were slower and had a higher baseline blood pressure gained the most from the training regimen and race.

Never too late to change

Senior author Dr. Charlotte H. Manisty, who works at the Institute of Cardiovascular Science at University College London and Barts Heart Centre in London, United Kingdom, comments on the findings:

Our study shows it is possible to reverse the consequences of aging on our blood vessels with real-world exercise in just 6 months.”

Dr. Charlotte H. Manisty

“These benefits were observed in overall healthy individuals across a broad age range,” she adds, “and their marathon times are suggestive of achievable exercise training in novice participants.”

People with greater arterial stiffness and hypertension may benefit even more from this form of exercise, although future studies would need to test this theory.

However, it is not possible to conclude that exercise alone produced the above effects.

The more healthful lifestyle choices that often accompany marathon training, such as a better diet and sleeping pattern, may have had a part to play.

It is also possible that some participants adopted a different training regimen to the recommended plan, meaning that further research will need to take a standardized approach.

Nevertheless, the findings highlight “the importance of lifestyle modifications to slow the risks associated with aging, especially as it appears to never be too late as evidenced by our older, slower runners,” Dr. Manisty states.

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